This study was undertaken to assess the level of readiness of higher education institutions (HEIs) for horizontal typology, institutional sustainability, and quality assurance in the key result areas (KRAs) for the enhancement of mechanisms, systems, and policies for the HEIs’ effective operation. It is a descriptive correlational design using the modified self-evaluation document (SED). The study showed that all the seven HEIs that participated in this study had been operating for 40 years and above, offering more than sixteen program courses with more than sixteen accredited programs. Four of the HEIs were Level 2 in accreditation status and five were ISO Certified. The level of readiness of HEIs for horizontal typology was moderately ready, which means the HEIs need some improvements in horizontal typology.  The most identified challenges affecting the level of readiness of HEIs in horizontal typology were the lack of innovation, technology, and sustainability; the lack of administrative strategies, leadership competencies, and management skills; and the lack of financial allocation for institutional development and advancements, respectively. There is no significant relationship between the institutional profile and terms of observing the standards in the KRAs. The study recommends further re-assessing the level of readiness of the HEIs in terms of documentation/evidence, observance for the improvement of the systems, processes and practices towards a more effective and efficient delivery of academic services to young people by conducting the more focused study in every KRAs and institutional self-assessment as future researches for the further improvement of the operations of HEIs.